DrugRepV_1872 | PHA-690509 | NA | Cancer | Zika virus | MR766 (1947 Ugandan strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1873 | PHA-690509 | NA | Cancer | Zika virus | FSS13025 (2010 Cambodian strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1874 | PHA-690509 | NA | Cancer | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1875 | PHA-690509 | NA | Cancer | Zika virus | MR766 (1947 Ugandan strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1876 | PHA-690509 | NA | Cancer | Zika virus | FSS13025 (2010 Cambodian strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1877 | PHA-690509 | NA | Cancer | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1878 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | Approved | 27571349 |
DrugRepV_1879 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | Approved | 27571349 |
DrugRepV_1888 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | Approved | 27571349 |
DrugRepV_1889 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | Approved | 27571349 |
DrugRepV_1890 | PHA-690509 | NA | Cancer | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1891 | PHA-690509 | NA | Cancer | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1900 | PHA-690509 | NA | Cancer | Zika virus | FSS13026 | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1901 | Alvocidib | NA | Cancer | Zika virus | FSS13026 | NA | Western blot | Decrease (Decrease Band intensity) | Experimental | 27571349 |
DrugRepV_1902 | PHA-793887 | Anticancer | Cancer | Zika virus | FSS13026 | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1903 | Dinaciclib | Anticancer | Cancer | Zika virus | FSS13026 | NA | Western blot | Decrease (Decrease Band intensity) | Investigational | 27571349 |
DrugRepV_1904 | Seliciclib | Anticancer | Breast cancer | Lung cancer | Lymphoma | Multiple myeloma | Leukemia | Zika virus | FSS13026 | NA | Western blot | Decrease (Decrease Band intensity) | Investigational | 27571349 |
DrugRepV_1905 | PHA-690509 | NA | Cancer | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1906 | Alvocidib | NA | Cancer | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | Experimental | 27571349 |
DrugRepV_1907 | PHA-793887 | Anticancer | Cancer | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1908 | Dinaciclib | Anticancer | Cancer | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | Investigational | 27571349 |
DrugRepV_1909 | Seliciclib | Anticancer | Breast cancer | Lung cancer | Lymphoma | Multiple myeloma | Leukemia | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | Investigational | 27571349 |
DrugRepV_1943 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Zika virus | SZ-WIV01 | NA | Western blot | Decrease (100 Band Intensity) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1954 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Zika virus | SZ-WIV01 | NA | Western blot | Decrease (100 Band Intensity) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_3004 | Imipramine | Nervous System | Depression | Chikungunya virus | La Reunion strain | NA | Western blot | Decrease (100 %) | Approved | 28600536 |
DrugRepV_3005 | Imipramine | Nervous System | Depression | Chikungunya virus | La Reunion strain | NA | Western blot | Decrease (100 %) | Approved | 28600536 |
DrugRepV_3006 | Imipramine | Nervous System | Depression | Chikungunya virus | La Reunion strain | NA | Western blot | Decrease (100 %) | Approved | 28600536 |
DrugRepV_3068 | Abamectin | NA | Helmintic infection | Chikungunya virus | CHIKV-Rluc | NA | Western blot | Decrease | Terminated | 26752081 |
DrugRepV_3069 | Abamectin | NA | Helmintic infection | Chikungunya virus | CHIKV-Rluc | NA | Western blot | Decrease | Terminated | 26752081 |
DrugRepV_3070 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Chikungunya virus | CHIKV-Rluc | NA | Western blot | Decrease | Approved, Investigational, Vet approved | 26752081 |
DrugRepV_3071 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Chikungunya virus | CHIKV-Rluc | NA | Western blot | Decrease | Approved, Investigational, Vet approved | 26752081 |
DrugRepV_3072 | Abamectin | NA | Helmintic infection | Chikungunya virus | CHIKV-Rluc | NA | Western blot | Decrease | Terminated | 26752081 |
DrugRepV_3073 | Abamectin | NA | Helmintic infection | Chikungunya virus | CHIKV-Rluc | NA | Western blot | Decrease | Terminated | 26752081 |
DrugRepV_3074 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Chikungunya virus | CHIKV-Rluc | NA | Western blot | Decrease | Approved, Investigational, Vet approved | 26752081 |
DrugRepV_3075 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Chikungunya virus | CHIKV-Rluc | NA | Western blot | Decrease | Approved, Investigational, Vet approved | 26752081 |
DrugRepV_3150 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Western blot | Decrease | NA | 23275491 |
DrugRepV_3151 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-122508 | NA | Western blot | Decrease | NA | 23275491 |
DrugRepV_3152 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Western blot | Decrease | NA | 23275491 |
DrugRepV_3153 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Western blot | Decrease | NA | 23275491 |
DrugRepV_3154 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-122508 | NA | Western blot | Decrease | NA | 23275491 |
DrugRepV_3155 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-122508 | NA | Western blot | Decrease | NA | 23275491 |
DrugRepV_3205 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Western blot | Decrease (Capsid protein Protein expression) | Investigational | 26384169 |
DrugRepV_3206 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Western blot | Decrease (E1 protein Protein expression) | Investigational | 26384169 |
DrugRepV_3207 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Western blot | Decrease (pE2 protein Protein expression) | Investigational | 26384169 |
DrugRepV_3208 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Western blot | Decrease (E2 protein Protein expression) | Investigational | 26384169 |
DrugRepV_3209 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Western blot | Decrease (nsP2 protein Protein expression) | Investigational | 26384169 |
DrugRepV_3210 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Western blot | Decrease (nsP3 protein Protein expression) | Investigational | 26384169 |
DrugRepV_3225 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VS | NA | Western blot | Decrease (pE2 protein expression Protein expression) | Investigational | 26384169 |
DrugRepV_3226 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VS | NA | Western blot | Decrease (E2 protein expresion Protein expression) | Investigational | 26384169 |
DrugRepV_3227 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226AS | NA | Western blot | Decrease (pE2 protein expression Protein expression) | Investigational | 26384169 |
DrugRepV_3228 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226AS | NA | Western blot | Decrease (E2 protein expresion Protein expression) | Investigational | 26384169 |
DrugRepV_5090 | S-Nitroso-N-acetylpenicillamine | NA | NA | Crimean-Congo hemorrhagic fever virus | IbAr 10200 | NA | Western blot | Decrease | NA | 16632039 |
DrugRepV_5092 | IFN-alpha | Antiviral | Hepatitis C virus | Leukemia | Melanoma | Crimean-Congo hemorrhagic fever virus | IbAr 10200 | NA | Western blot | Decrease | Investigational | 16372299 |
DrugRepV_5093 | IFN-alpha | Antiviral | Hepatitis C virus | Leukemia | Melanoma | Crimean-Congo hemorrhagic fever virus | IbAr 10200 | NA | Western blot | Decrease | Investigational | 16372299 |
DrugRepV_5149 | PF-4708671 | NA | NA | Rift Valley fever virus | MP12 | NA | Western blot | Decrease | NA | 29652799 |
DrugRepV_5151 | PF-4708671-BI-D1870 | NA | NA | Rift Valley fever virus | MP12 | NA | Western blot | Decrease | NA | 29652799 |
DrugRepV_5153 | SB203580 | NA | NA | Rift Valley fever virus | MP12 | NA | Western blot | No significant effect | NA | 29652799 |
DrugRepV_5155 | PD0325901 | NA | Melanoma | Solid Tumour | Solid Tumors | Advanced Cancer | Breast Neoplasms | Rift Valley fever virus | MP12 | NA | Western blot | Decrease | Investigational | 29652799 |
DrugRepV_5166 | Rapamycin | Antineoplastic and Immunomodulating Agents; Sensory Organ | Prophylaxis of organ rejection in patients receiving renal transplants | Rift Valley fever virus | MP12 | NA | Western blot | Decrease | Approved, Investigational | 28442428 |
DrugRepV_5754 | Fenretinide | Anticancer | Prostate cancer | Breast cancer | Macular degeneration | Dengue virus | NGC | | Western blot | Decrease (100 %) | Investigational | 25313218 |
DrugRepV_5755 | Fenretinide | Anticancer | Prostate cancer | Breast cancer | Macular degeneration | Dengue virus | NGC | | Western blot | Decrease (100 %) | Investigational | 25313218 |
DrugRepV_5794 | Lanatoside C | Cardiovascular agents | Arrhythmia | Dengue virus | Singapore isolates | | Western blot | Decrease (6.7 Fold) | Experimental | 25251726 |
DrugRepV_5795 | Lanatoside C | Cardiovascular agents | Arrhythmia | Dengue virus | Singapore isolates | | Western blot | Decrease (6.3 Fold) | Experimental | 25251726 |
DrugRepV_5801 | Geneticin | Antibacterial | Bacterial infections | Dengue virus | NA | | Western blot | Decrease (100 %) | Experimental | 19501253 |
DrugRepV_5802 | Geneticin | Antibacterial | Bacterial infections | Dengue virus | NA | | Western blot | Decrease (80 %) | Experimental | 19501253 |
DrugRepV_5858 | Narasin | Antibacterial | Parasitic and bacterial infections | Dengue virus | NA | | Western blot | Decrease | Experimental | 22155902 |
DrugRepV_5859 | Narasin | Antibacterial | Parasitic and bacterial infections | Dengue virus | NA | | Western blot | Decrease | Experimental | 22155902 |
DrugRepV_5863 | N-Desmethylclozapine | Antipsychotic | Schizophrenia | Schizoaffective disorders | Dengue virus | NA | | Western blot | Decrease (Decrease Band intensity) | Investigational | 27572397 |
DrugRepV_5864 | Fluoxetine | Nervous System | Major depressive disorder | Bulimia nervosa | Obsessive-compulsive disorder | Premenstrual dysphoric disorder | Panic disorder with or without agoraphobia | Dengue virus | NA | | Western blot | Decrease (Decrease Band intensity) | Approved, Vet approved | 27572397 |
DrugRepV_5865 | Salmeterol | Respiratory System | Asthma | Chronic obstructive pulmonary disease | Dengue virus | NA | | Western blot | Decrease (Decrease Band intensity) | Approved | 27572397 |
DrugRepV_5932 | Prochlorperazine Novamin | Nervous System | Nausea | Vomiting | Schizophrenia | Dengue virus | New Guinea C | | Western blot | Decrease (100 %) | Approved | 25028694 |
DrugRepV_5933 | Prochlorperazine Dimaleate | Nervous System | Nausea | Vomiting | Schizophrenia | Dengue virus | New Guinea C | | Western blot | Decrease (100 %) | Approved | 25028694 |
DrugRepV_5978 | Castanospermine | Antiviral | Dengue and Parainfluenza | Dengue virus | 16681 | | Western blot | Decrease | Experimental | 15994763 |
DrugRepV_6015 | N-nonyl-deoxynojirimycin | NA | NA | Dengue virus | PL046 | | Western blot | Decrease (Decrease Band Intensity) | NA | 11907199 |
DrugRepV_6016 | N-nonyl-deoxynojirimycin | NA | NA | Dengue virus | PL046 | | Western blot | Decrease (Decrease Band Intensity) | NA | 11907199 |
DrugRepV_6026 | Saracatinib | Anticancer | Cancer | Dengue virus | New Guinea C | | Western blot | Decrease (Decrease expression of C protein Band Intensity) | Investigational | 23616652 |
DrugRepV_6027 | Saracatinib | Anticancer | Cancer | Dengue virus | New Guinea C | | Western blot | Decrease (Decrease expression of E protein Band Intensity) | Investigational | 23616652 |
DrugRepV_6028 | Saracatinib | Anticancer | Cancer | Dengue virus | New Guinea C | | Western blot | Decrease (Decrease expression of NS3 and NS5 protein Band Intensity) | Investigational | 23616652 |
DrugRepV_6029 | Dasatinib | Antineoplastic and Immunomodulating Agents | Cancer | Dengue virus | New Guinea C | | Western blot | Decrease (Decrease expression of C protein Band Intensity) | Approved | 23616652 |
DrugRepV_6030 | Dasatinib | Antineoplastic and Immunomodulating Agents | Cancer | Dengue virus | New Guinea C | | Western blot | Decrease (Decrease expression of E protein Band Intensity) | Approved | 23616652 |
DrugRepV_6031 | Dasatinib | Antineoplastic and Immunomodulating Agents | Cancer | Dengue virus | New Guinea C | | Western blot | Decrease (Decrease expression of NS3 and NS5 protein Band Intensity) | Approved | 23616652 |
DrugRepV_7111 | N-nonyl-deoxynojirimycin | NA | NA | Japanese encephalitis virus | RP-9 | | Western blot | No significant effect (No significant effect Band Intensity) | NA | 11907199 |
DrugRepV_7112 | N-nonyl-deoxynojirimycin | NA | NA | Japanese encephalitis virus | RP-9 | | Western blot | No significant effect (No significant effect Band Intensity) | NA | 11907199 |
DrugRepV_7318 | NITD008 | Antiviral | NA | Japanese encephalitis virus | JEV?Pac?Rluc?Rep | | Western blot | Decrease (NA %) | NA | 28779235 |
DrugRepV_7322 | N-(6-methanesulfonyl-1,3-benzothiazol-2-yl)-4-[(4-nitro-1H-pyrazol-1-yl)methyl]benzamide | NA | NA | Japanese encephalitis virus | P3 | | Western blot | Decrease (70.1 %) | NA | 27679979 |
DrugRepV_7323 | N-[6-({[(thiophen-2-yl)formamido]methanethioyl}amino)-1,3-benzothiazol-2-yl]butanamide | NA | NA | Japanese encephalitis virus | P3 | | Western blot | Decrease (94.8 %) | NA | 27679979 |
DrugRepV_7374 | Luteolin | NA | NA | Japanese encephalitis virus | SX09S01 | | Western blot | Decrease | NA | 27126774 |
DrugRepV_7386 | Dehydroepiandrosterone | NA | Schizophrenia | Japanese encephalitis virus | NT113 | | Western blot | Decrease | Approved | 16099910 |
DrugRepV_8311 | Esomeprazole | Alimentary Tract and Metabolism | Acid-reflux disorders (GERD) and peptic ulcer disease | Human immunodeficiency virus | NA | | Western blot | Decrease (50 %) | Approved | 32132561 |
DrugRepV_8312 | Lansoprazole | Alimentary Tract and Metabolism | Gastric ulcers, active duodenal ulcers, erosive reflux oesophagitis, symptomatic gastroesophageal reflux disease | Human immunodeficiency virus | NA | | Western blot | Decrease (50 %) | Approved, Investigational | 32132561 |
DrugRepV_8313 | Pantoprazole | Alimentary Tract and Metabolism | Gastroesophageal reflux disease | Human immunodeficiency virus | NA | | Western blot | Decrease (50 %) | Approved | 32132561 |
DrugRepV_8314 | Rabeprazole | Alimentary Tract and Metabolism | Acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevention of gastroinetestinal bleeds with NSAID use | Human immunodeficiency virus | NA | | Western blot | Decrease (50 %) | Approved, Investigational | 32132561 |
DrugRepV_8315 | Tenatoprazole | NA | NA | Human immunodeficiency virus | NA | | Western blot | Decrease (50 %) | NA | 32132561 |